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Annual Deaths

CANNABINOID DRUG INTERACTION

Given the increasing acceptance and prevalence of cannabis as a therapeutic option, it’s important for physicians and patients to understand how various cannabis components interact with commonly consumed pharmaceuticals.
Project CBD, a California-based educational non-profit, has published an in-depth primer on Cannabinoid-Drug Interactions for health professionals, patients, and public policy-makers. The 33-page report, summarized below, is available for free download below.
The Project CBD primer includes a discussion of various “substrates” or drugs that are metabolized by cytochrome P450, a large family of non-specific enzymes that are involved in breaking down an estimated 60 to 80 percent of all pharmaceuticals. Cytochrome P450 enzymes may be inhibited or amplified by CBD, THC and other plant cannabinoids, thereby reducing or prolonging the activity of another drug.
By suppressing or inducing specific cytochrome P450 enzymes, CBD and THC can alter how one metabolizes a wide range of substances. Much depends on the particular substrate involved in the drug interaction. Some pharmaceuticals, known as “prodrugs,” don’t become functional until they are metabolized into an active component. If CBD or THC inhibits the breakdown of a prodrug, the latter will remain inactive – whereas inhibiting the metabolism of a regular drug will result in higher blood levels of the active substance.
Several variables make precise predictions about drug interactions difficult, even for practiced physicians. “It is much easier to assess whether drug interactions are likely than to predict their exact effect,” the Project CBD primer asserts.


cannabinoid-drug-interactions_2018-10-11.pdf
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​Void Where Prohibited by Law.

Hemp is defined by Section 10111 of the US Farm Bill: The term ‘hemp’ means the plant Cannabis sativa L. and any part of that plant, including the seeds thereof and all derivatives, extracts, cannabinoids, isomers, acids, salts, and salts of isomers, whether growing or not, with a delta-9 tetrahydrocannabinol concentration of not more than 0.3 percent on a dry weight basis.”
CBD Nutritional only sells products that meet the Federal definition of industrial hemp (Dried hemp and hemp products containing less than .3% Delta 9 THC).
Legal Disclaimer: The CBD (Cannabidiol) contained in CBD Nutritional products has been grown, processed and produced in accordance to the 2014 Farm Bill, Section 7606. This product is legal for marketing in the United States pursuant to Sec. 7606. The Food and Drug Administration (FDA) considers non-THC based hemp products to be "food based" and therefore legal without a medical marijuana license.
Our products are not intended to diagnose, treat, prevent, or cure any disease. Due to restrictions and limitations we are not making any medical claims whatsoever. As a user you acknowledge that the information contained within this website is not intended to be nor is to be treated as a substitute for professional medical advice relative to a specific medical conditions. As with all supplements it is important to let your doctor know what you are taking. ​

These statements have not been evaluated by The Food and Drug Administration. Our website and CBD products are not intended to diagnose, treat, cure or prevent any disease. Under no circumstances does our website CBD Nutritional imply that any and all products and formulas are meant to diagnose, treat, cure or prevent any diseases.

CBD Nutritional does not sell or distribute any products that are in violation of the United States Controlled Substances Act (US.CSA).


CBD Nutritional / CBD Store AZ
(602) 292-6133
3314 N 3rd Street, Phoenix, AZ 85012
cbdnutritional@gmail.com or cbdstoreaz@gmail.com
  • home
  • SHOP NOW
  • CBD STORE AZ
  • QUALITY CONTROL
  • CBD Life Blog
  • Cbd health studies
  • CBD FAQ's
    • KNOW YOUR SOURCE/SUPPLIER
    • DOSING
    • Endocannabinoid Deficiency Theory
    • Hemp Cannabinoids & Terpenes
    • CBG
    • CBD Glossary
    • Full Spectrum vs Isolate
    • Topical ? Transdermal ?
    • Vaping Pure CBD
    • Smoking Hemp Flower >
      • Traveling with CBD
    • Cannabinoid Drug Interaction
    • CBD & Pets
    • CBD for Anxiety
    • CBD for Depression
    • CBD for Diabetes
    • CBD FOR WELLNESS
    • CBD 4 BEAUTY
  • Wellness Beyond CBD
    • DETOX FOR WELLNESS
    • Anti-Aging CBD
    • EMF PROTECTION
    • NUTRITION FOR WELLNESS
    • EXERCISE FOR WELLNESS
  • Website Policy
    • Terms and Conditions
    • Privacy Policy
  • Current CBD News