When CBD doesn't work--Why?

This just boggles my mind. Why doesn't it work for everyone?  If we all have and endocannibinoid system and receptor sites why?  Is there damage, are the receptors clogged and not talking with the brain?  If so what is the clog?  Environmental toxins?  Diet?  Pharmaceuticals?  I really want to know what this is.  It is usually someone claiming to have fibromyalgia, who have had numerous surgeries.  Is it anesthesia?  Okay, this may be a bit odd, but I really want to understand this, so I ask a psychic medium for help.  She told me the following:  1) That 20+% will not get relief from anything--that it is a karmic obligation!  2) 79% can get relief with energy work, reiki, laying on of hands, very gentle touch with an application of oil will put a "layer between them and the world".  4) That their nerves are stripped and this may be an identity psychological pattern to be released, (they feel emotionally ripped off).  5) They require stillness, quiet, peaceful environment, rest, chemical free environment and non-restrictive clothing.  6) Gentle detox protocols and very light EFT, essential oils and CBD would be beneficial.  

I would love for all my fibromyalgia suffers to give our topicals a try as I have been getting good results with CBD interacting with CB1 receptor sites within the skin.    

Much gratitude to TK for her insights of fibromyalgia and CBD.